NGOs are the helping hand they are actually helping out those who need them. And this process is not a give and take but they really want to do something for them. And I am also the part of it. And I feel blessed and happy when I work for them. The Basic life process is helping others and also becoming a personality we want to be in life. Your satisfaction are not in big gifts or expensive things all you need is love and satisfaction and that you will get when you do something for others more than for yourself.
As your happiness is all around you and in other people than you yourself . Because all you need to do something for others either you get or not get anything out of it. But you will still do it as it gave you happiness which you will find no where and for that you can do anything. This is the reason why people want to be around people irrespective of their choices are very much different expectations are not same. Their still a bound which we cannot find out after so much haterate and ignorance. Our moral is down everyday with the fact that we are useless and never can achieve our goals.
But one thing always in our minds that we can do it because we believe in us. And that believe only comes from people who demotivate us to do better in our life. We are here just because of them. As your failures are the reason of your success and those who criticised you for your failures will make you more strong and Independent and make you realise the importance of your love ones and your own people. You will understand who is your own or who are just fake. So helping make you connect to them as you know you were also there at one time and there was noone except your family. That the motivation and dedication that encourage you do something for others.
Several investigations have revealed a deterioration of mental health concerns among people of all ages since the commencement of the Covid-19 epidemic. Michele Mary Bernadine investigates the situation of mental health in India, the economic burden of the mental health problem, and the extent to which legislation and current State capability are ready to manage this issue in this post. In 2017, India’s President, Ram Nath Kovind, declared that the country was “on the verge of a mental health crisis.” According to one research, 14 percent of India’s population suffered from mental health problems in the same year, with 45.7 million suffering from depressive disorders and 49 million suffering from anxiety disorders. The Covid-19 epidemic has exacerbated this mental health catastrophe, with reports from throughout the world indicating that the Virus and accompanying lockdowns were having a severe impact on the populace — particularly on young people.
LEGISLATION AND CONSTRUCTION CAPABILITY OF THE STATE
The Mental Healthcare Act of 2017 has numerous clauses aimed at improving India’s mental health. The Mental Healthcare Act of 1987 is repealed by this Act, which was criticised for failing to recognise the rights and agency of persons suffering from mental illness (Mishra and Galhotra 2018). This involves establishing Central and State Mental Health Authorities (SMHA), which would focus on constructing solid infrastructure, including the registration of mental health practitioners and the implementation of service-delivery guidelines. Although the Act requires states to establish an SMHA within nine months of the Act’s passage, only 19 of the 28 states had done so as of 2019. In accordance with WHO recommendations, the National Mental Health Programme (NMHP)2 was established in 1982 to provide mental health treatments as part of the general healthcare system. Although the initiative has been effective in increasing community access to mental health treatment, resource restrictions and a lack of infrastructure have restricted its impact (Gupta and Sagar 2018). Only a few states had a specific line item in their budgets for mental health infrastructure as of 2021. 3 Budget projections for the NMHP increased from Rs. 3.5 million in 2017-18 to Rs. 5 million in 2018-19 after the Act was passed in 2017. This number, however, was cut to Rs. 4 million in 2019-20 and has stayed at the same level in succeeding years – even in 2021-22, when various studies have suggested a worsening of mental health difficulties amid the Covid-19 epidemic. Emerging evidence suggests that during the Covid-19 pandemic, women have higher levels of psychological stress than the urban poor (Afridi et al. 2020), and households with migrant workers in rural areas – who were particularly hard hit by the lockdown restrictions – have a higher incidence of mental health issues than those without migrants (Sarin et al. 2021). The lockdowns also had a significant impact on students, who had to adjust to a new learning medium and setting, as well as raised fears about their future prospects. During the epidemic, the government launched ‘Manodarpan,’ an online portal featuring an interactive online chat option, a list of mental health practitioners, and a hotline number to give psychological assistance to students. Developed nations spend 5-18% of their yearly healthcare expenditure on mental health, while India spends just 0.05%. (Organization for Economic Co-operation and Development, 2014). The yearly budget for 2018 and 2019 included funding for the National Institute of Mental Health Rehabilitation. The institution was established in 2018 with the goal of increasing human resource capacity and doing research in the field of mental health. Furthermore, the government yearly sponsors the Lokopriya Gopinath Borolo Regional Institute of Mental Health and NIMHANS, all of which are under the Ministry of Health and Family Welfare. Although NIMHANS claims to offer inexpensive and accessible mental healthcare to all individuals in need, these efforts remain regionally isolated because the organisation is based in a single city (Bengaluru). Initiatives like the NIMHANS Centre for Well Being, which offers low-cost therapy sessions from experienced experts, would be a big help if they were spread to additional regions around the country, but their influence is now restricted to an urban metropolis.
After the implementation of the Act, the Economic Survey of India has yet to address mental health in a substantive manner, with the only mention of mental health in this period being a cursory reference in the context of information asymmetry in healthcare and changes in the approach to medicine during the Covid-19 pandemic (Economic Survey 2020-21). In contrast to the President’s remark in 2017, the administration has recently refused to accept the severity of mental health illnesses in India as approaching a “pandemic.” Questions in parliament about efforts to improve mental health for specific demographic groups (for example, the elderly) elicit a standard response – referring to NIMHANS initiatives to improve general mental health and the NMHP/DMHP – with no mention of any targeted interventions or plans to do so. Recognizing the scope of the problem would be the first step in addressing the country’s mental health crisis. According to an Indian Psychiatry Society poll, 20 percent more individuals have suffered from poor mental health since the start of the Covid-19 epidemic.
Cancer is a collection of diseases that may never be totally cured, but scientists are confident that vaccinations, personalized treatment, and wise lifestyle choices can help prevent and treat a considerably larger proportion of instances than is presently the case. We questioned three cancer experts for their ideas on treating cancer: Nobel winner Professor Harald Zur Hausen, Professor Walter Ricciardi, and Dr Elisabete Weiderpass. They are all members of the EU’s Horizon Europe cancer mission board, where they will assist create a clear aim for Europe in this field over the next decade. ‘Evidence of infections linked to cancer provides promise for avoiding up to half of all malignancies,’ says one researcher. If we will ever be able to cure cancer entirely, that is a question I cannot answer. We have a strong probability of dramatically lowering cancer incidence. However, the incidence, or occurrence, of cancer is now growing internationally. Cancer patients’ mortality is marginally reducing; however the increase in incidence is not compensating for the death drop. There are still many instances reported each year, and if we truly want to do something about cancer in the future, we must halt the trend. We know that several cancer risk factors are avoidable. At the time, we also know that infections have a role in around 20% of malignancies. We can effectively immunise patients against these types of cancer and virtually eradicate it, particularly in cases where vaccines are currently available, such as Hepatitis B (a cause of liver cancer) and Human Papillomavirus (which Prof. zur Hausen discovered is linked to cervical cancer).
We think we have evidence that infectious episodes cause at least 30% of all human malignancies. This at least gives optimism that new approaches will be discovered in the near future that will lead to long-term protection from those illnesses – notably colon cancer, breast cancer, and prostate cancer, where evidence is emerging that specific viral episodes have a role. We just found a whole new class of infectious pathogens produced from plasmids. Plasmids are bacterial mini-chromosomes that are found in a substantial majority of colon cancer patients. These are infections that can last for decades, generating chronic inflammations, and these inflammations are the source of oxygen radicals and mutation events in cells that can lead to cancer formation. We have sequenced all of the (plasmid) genomes that we have uncovered so far, and what we discovered surprised us since it did not reflect viral or bacterial sequences. They are slightly altered bacterial plasmids that originated in certain bacteria but have learned to reproduce independently in bovine and human cells. So, in my perspective, this will hopefully allow for new methods to prevent and, in the long run, therapy of these extremely frequent malignancies. The most challenging issue is to do more fundamental research and emphasize preventative efforts to reduce the frequency of cancer occurrence by preventing cancer precursor lesions with surgical procedures. To cure cancer, we need to enhance the therapy regimen. And we need to develop some mechanism to provide long-term, lifelong patient protection. Because cancer is a broad term for various diseases, we cannot take a comprehensive approach – a cure for every form of cancer – but we may devise a broad strategy. It requires collaboration among several stakeholders, not just in the health sector, but also in the social sector, because many of the behaviours that contribute to the start of cancer are changeable via lifestyle and preventive. We must also take advantage of technological advancements. I’m optimistic we’ll find a better way to combat this sickness. We now have the ability to collect a large amount of data that, in theory, maybe tied to genome sequencing, because, as far as we know, some malignancies are genetically determined. We know that the majority are caused by five variables, four of which are behaviors – alcohol and cigarette use, eating too much and not getting enough physical activity, and pollution. Digital technology may include a large amount of data, ranging from the most general to the most detailed features of a single person.
Understanding a person’s unique traits allows us to create a more personalized and precision-targeted strategy, avoiding what happens presently, when we supply a single medicine, for example, for every type of breast cancer. We know that causes adverse effects in some women who do not benefit from the medicine. So, taking a look at a subset of women with breast cancer is the route we need to take.
Immunotherapy (in which the patient’s immune system is stimulated to target the cancer) has also shown astounding outcomes. Some malignancies, such as lung cancer and metastatic melanoma, were formerly untreatable; however, we now have the ability to treat them and, in some circumstances, provide a major cure for the disease. I believe we may be positive on this front as well. Cancer is a disease family. There are over a hundred distinct forms of cancer. Some varieties are treatable and cured, particularly when diagnosed early and in wealthier nations, while others do not know how to cure.
We already know how to identify and treat certain cancers, such as early-stage breast cancer, testicular cancer, and some forms of leukemia, and we also know how to treat them exceedingly well. There are numerous cancer forms where significant progress has been achieved, yet there are several cancer types where we don’t know what to do. . Prostate cancer is a reasonably prevalent cancer type for which we still don’t know the best approaches to identify it early or whether it’s even helpful to detect it early. We don’t have effective screening methods, and we don’t know how to tell the difference between slow-growing varieties that don’t require much intervention and fast-growing ones that do. So prostate cancer is undoubtedly one cancer that poses a significant public health problem since it affects a huge number of men. With a large rise in the number of cancer patients projected over the coming decades owing to increased life expectancy, governments are being urged to establish cancer prevention and control programmers more swiftly and rigorously, as 30-40% of malignancies are avoidable (in European countries; for other countries, the proportion of preventable cancers is even higher). What regular Europeans can do is learn the European Cancer Code. These are 12 evidence-based methods for lowering your cancer risk and detecting certain tumours early. Smoking, for example, is still responsible for half of all avoidable cancers in Europe. Other examples include an unsuitable diet that lacks fruits and vegetables and a diet that leads to obesity.
recent breakthroughs in cancer research
CAR-T TREATMENT FOR LEAUKIMIA
CAR-T treatment uses gene therapy techniques not to fix disease-causing genes but to turbocharge T cells, immune system soldiers that cancer too often can evade. Researchers filter those cells from a patient’s blood, reprogram them to harbor a “chimeric antigen receptor” or CAR that zeroes in on cancer, and grow hundreds of millions of copies. Returned to the patient, the revved-up cells can continue multiplying to fight disease for months or years.
It’s a completely different way to harness the immune system than popular immunotherapy drugs called “checkpoint inhibitors” that treat a variety of cancers by helping the body’s natural T cells better spot tumors. CAR-T cell therapy gives patients stronger T cells to do that job.