Tag: horse shoe crab

The Living Fossils.

These are those few animals who have defeated the tides of time by staying alive through chains of thick and thins millions and millions of years without accepting any evolutionary change in their basic body structure and habitat and every thing and features concerned with them.

Horseshoe crab

These are marine and brackish water arthropods of the family Limulidae, suborder Xiphosurida, and order Xiphosura. Their popular name is a misnomer, as they are not true crabs, which are crustaceans.Horseshoe crabs live primarily in and around shallow coastal waters on soft sandy or muddy bottoms. They tend to spawn in the intertidal zone at spring high tides. They are commonly eaten in Asia, and used as fishing bait, in fertilizer and in science (especially Limulus amebocyte lysate). In recent years, population declines have occurred as a consequence of coastal habitat destruction and overharvesting. The entire body of the horseshoe crab is protected by a hard carapace. It has two compound lateral eyes, each composed of about 1,000 ommatidia, plus a pair of median eyes that are able to detect both visible light and ultraviolet light, a single endoparietal eye, and a pair of rudimentary lateral eyes on the top. The latter become functional just before the embryo hatches. Also, a pair of ventral eyes is located near the mouth, as well as a cluster of photoreceptors on the telson.

Coelacanth

The coelacanths constitute a now-rare order of fish that includes two extant species in the genus Latimeria: the West Indian Ocean coelacanth (Latimeria chalumnae) primarily found near the Comoro Islands off the east coast of Africa and the Indonesian coelacanth (Latimeria menadoensis). They follow the oldest-known living lineage of Sarcopterygii (lobe-finned fish and tetrapods), which means they are more closely related to lungfish and tetrapods than to ray-finned fish. They are found along the coastline of Indonesia and in the Indian Ocean. The West Indian Ocean coelacanth is a critically endangered species.

Coelacanths belong to the subclass Actinistia, a group of lobed-finned fish related to lungfish and certain extinct Devonian fish such as osteolepiforms, porolepiforms, rhizodonts, and Panderichthys. Coelacanths were thought to have become extinct in the Late Cretaceous, around 66 million years ago, but were rediscovered in 1938 off the coast of South Africa.The coelacanth was long considered a “living fossil” because scientists thought it was the sole remaining member of a taxon otherwise known only from fossils, with no close relations alive, and that it evolved into roughly its current form approximately 400 million years ago.However, several recent studies have shown that coelacanth body shapes are much more diverse than previously thought.

Nautilus

The nautilus is a pelagic marine mollusc of the cephalopod family Nautilidae, the sole extant family of the superfamily Nautilaceae and of its smaller but near equal suborder, Nautilina.It comprises six living species in two genera, the type of which is the genus Nautilus. Though it more specifically refers to species Nautilus pompilius, the name chambered nautilus is also used for any of the Nautilidae. All are protected under Nautilidae, both extant and extinct, are characterized by involute or more or less convolute shells that are generally smooth, with compressed or depressed whorl sections, straight to sinuous sutures, and a tubular, generally central siphuncle. Having survived relatively unchanged for hundreds of millions of years, nautiluses represent the only living members of the subclass nautiloidea, and are often considered “living fossils”.

The word nautilus is derived from the Greek ναυτίλος nautílos and originally referred to the paper nautiluses of the genus Argonauta, which are actually octopuses. The word nautílos literally means “sailor”, as paper nautiluses were thought to use two of their arms as sails.

Blood Harvest.

So we all know about horse shoe crabs those infamous hideous looking gentle and harmless organism sometimes termed as the living fossil because of their presence on our planet since millions and millions of years. So blood harvest happens on the blood of a horse shoe crab which has a striking baby blue colored blood due to presence of copper rich haemocyanin agents(like we have iron rich haemoglobin).The marvelous thing about horseshoe crab blood, though, isn’t the color. It’s a chemical found only in the amoebocytes of its blood cells that can detect mere traces of bacterial presence and trap them in inescapable clots. To take advantage of this biological idiosyncrasy, pharmaceutical companies burst the cells that contain the chemical, called coagulogen. Then, they can use the coagulogen to detect contamination in any solution that might come into contact with blood. If there are dangerous bacterial endotoxins in the liquid—even at a concentration of one part per trillion—the horseshoe crab blood extract will go to work, turning the solution into what scientist Fred Bang, who co-discovered the substance, called a “gel.”

“This gel immobilized the bacteria but did not kill them,” Bang wrote in the 1956 paper announcing the substance. “The gel or clot was stable and tough and remained so for several weeks at room temperature.”If there is no bacterial contamination, then the coagulation does not occur, and the solution can be considered free of bacteria. It’s a simple, nearly instantaneous test that goes by the name of the LAL, or Limulus amebocyte lysate, test (after the species name of the crab, Limulus polyphemus).The LAL testreplaced the rather horrifying prospect of possibly contaminated substances being tested on “large colonies of rabbits.” Pharma companies didn’t like the rabbit process, either, because it was slow and expensive.

The only problem is that the companies need a large supply of the blood of live crabs. Horseshoe crabs live on the seafloor, near the shore. When they want to mate, they swim into very shallow water, and horseshoe crab collectors wade along, snatching the crabs out of their habitat. The biomedical collectors are not the first to make use of the crabs’ bodies. As far back as colonial times, “cancerine fertilizer” was used to enrich fields. In the 20th century, though, this became an organized industry around the Delaware Bay. The crabs were steamed and then ground into meal for the fields. Others were fed to hogs. Millions of crabs were harvested.

After the biomedical horseshoe crab collectors get them back to a lab, they pierce the tissue around the animals’ hearts and drain up to 30 percent of the animals’ blood. The LAL is extracted from the blood, and can go for $15,000 per quart. Only five companies bleed the crabs: Associates of Cape Cod, Lonza, Wako Chemicals, Charles River Endosafe, and Limuli Labs .The horseshoe crabs are returned to the ocean a great distance from where they were initially picked up to avoid rebleeding animals. The whole process takes between 24 and 72 hours.The industry says that not that many of the animals die. Between 10 and 30 percent of the bled animals, according to varying estimates, actually die. We can imagine that it’s like us giving blood. The crabs get some apple juice and animal crackers and are fine soon thereafter.But some people have noticed problems. In the regions where horseshoe crabs are harvested in large numbers for biomedical purposes

Horseshoe crabs are an ancient animal, more than half a billion years old. They have their own ways of doing things, a fact we’ve been exploiting for decades.Our own species evolved a thousand times more recently, coming into our current anatomical form a couple hundred thousand years ago. Let’s hope we don’t wipe horseshoe crabs out after we finish cloning their ancient chemical wisdom.