Black Fungus: A Threat to Eyes

200,000 Amphotericin B doses used in black fungus treatment reaches India |  Latest News India - Hindustan Times

Mucormycosis, also known as black fungus, is a rare but dangerous Infection. Its caused by a group of molds called mucormycetes and often affects the sinuses, lungs, skin and brain. You can inhale the mold spores or come into contact with them in Things like soil, rotting produce or bread, or compost piles.

Symptoms of Mucormycosis

The symptoms of mucormycosis will depend on where in your body the fungus is growing.

 They may include:

  • Fever
  • Cough
  • Chest pain
  • Shortness of breath
  • Swelling on one side of your face
  • Headache
  • Sinus congestion
  • Black lesions on the bridge of your nose or the inside of your mouth
  • Belly pain
  • Nausea and vomiting
  • Gastrointestinal bleeding
  • Diarrhea

If your skin is infected, the area can look blistered, red, or swollen. It might turn black or feel warm or painful. The infection can also spread to other parts of your body through your blood. This is called disseminated mucormycosis. When this happens, the fungus can affect organs like your spleen and heart. In severe cases, you may have changes to your mental state or go into a coma. It can even be deadly.

Diagnosis and Treatment of Mucormycosis-

If you suspect mucormycosis, your doctor will give you a physical exam and ask about your medical history. Let them know if you’ve been around spoiled foods or other places in which fungal spores are often found. If it looks like you have a lung or sinus infection, your doctor may take a sample of the fluid from your nose or throat and send it to be tested in a lab. They might also do a tissue biopsy, taking out a small piece of infected tissue for testing. Your doctor may do imaging tests like CT or MRI scans to find out whether the infection has spread to your brain or other organs. If you’re diagnosed with mucormycosis, you should start treatment as soon as possible with prescription antifungal medications. These medicines stop the growth of the fungus, destroy it, and bring the infection under control.

You might take:

  • Amphotericin B
  • Isavuconazole
  • Posaconazole

You get these medications through a vein (intravenous or IV) or as pills that you swallow. Your doctor may start with high doses through an IV until the infection is under control, which can take several weeks. Then, you’ll switch to pills. Let your doctor know if a medication has troublesome side effects like stomach pain, heartburn, or trouble breathing. They may be able to change your treatment plan. In severe cases, your doctor may recommend surgery to remove infected or dead tissue to keep the fungus from spreading. This might include removing parts of your nose or eyes. It can be disfiguring. But it’s crucial to treat this life-threatening infection.

  • Blindness
  • Blood clots or blocked vessels
  • Nerve damage

Mucormycosis can be deadly without treatment. Because the infection is so rare, the exact mortality rate isn’t clear. But researchers estimate that overall, 54% of people with mucormycosis die. The likelihood of death depends on which part of the body is affected. The outlook is better for people who have sinus infections than it is for lung or brain infections.

Mucormycosis Prevention-

There is no way to avoid breathing in spores. But you can do a few Things to lower your chances of mucormycosis. It’s especially important if you have a health condition that raises your risk.

  1. Stay away from areas with a lot of dust or soil, like construction or excavation sites. If you have to be in these areas, wear a face mask like an N95.
  2. Avoid infected water. This can include floodwater or water-damaged buildings, especially after natural disasters like hurricanes or floods
  3. If you have a weakened immune system, avoid activities that involve dust and soil, like gardening or yard work.
  4. If you can’t, protect your skin with shoes, gloves, long pants, and long sleeves. Wash cuts or scrapes with soap and water as soon as you can.
  5. If you get mucormycosis, be sure to take your medications as directed. If side effects cause problems or the infection doesn’t get better, let your doctor know right away.

STAY HOME, STAY SAFE

MUCORMYCOSIS-A NEW ENTRANT

In the present condition where the second wave of coronavirus is alarming the whole world, something new has also barged in and is becoming a cause of worry-Mucormycosis. The Black fungus or “mucormycosis” in medical parlance is a new entrant into India, a rare and dangerous infection caused by a fungus by name “mucor” which can found on wet surfaces in general. These fungi are generally not harmful unless one has a weakened immune system. Black fungus is caused by mold found in moist places like soil or compost and are all pervasive in the environment. Black fungus attacks the respiratory tract. It is not contagious and does not spread from person to person. People get infected with mucromycosis , which are of several types, by breathing in fungal spores. Many people who were infected by COVID-19 were being infected by this deadly fungus due to low immune systems.

HOW DANGEROUS IS BLACK FUNGUS?

This disease is globally distributed , however its exact estimate couldn’t be placed due to insufficient data. Mucormycosis can become life threatening when it reaches the brain so doctors have to surgically remove eyes of patients to stop the infection from spreading too far and hence the infection needs to be detected soon and scraped off. The mortality rate considerably high in India due to delays in seeking medical attention and diagnosing the infection, and challenges and difficulties in managing the advanced stage of infection The estimates indicate that about 54% of people die of mucormycosis. Several people are also suffering from blindness as a result of this disease. The infection can also spread to other parts of your body through your blood. This is called disseminated mucormycosis. When this happens, the fungus affects organs like your spleen and heart. In severe cases, you might face several mental issues or also go into a coma. It can even be fatal at times.

WHO ARE ALL AT RISK?

  • Patients with Diabetes
  • People on immunosuppressants
  • People severely affected by COVID-19
  • People on ventilator support
  • Those with skin injury due to surgery or burns
  • Those who underwent organ transplant
  • HIV or AIDS
  • Long term steroid users
  • Premature birth or underweight birth

SYMPTOMS OF MUCORMYCOSIS

  • Fever
  • Shortness of breath
  • Chest pain
  • Cough
  • Swelling on one side of the face
  • Headache
  • Blurred or double vision
  • Sinus congestion
  • Pain in the belly
  • Nausea and vomiting
  • Diarrhea
  • Gastrointestinal bleeding
  • Blood in your stools
  • Black lesions on the bridge of the nose or inside the mouth

WHAT ARE THE COMPLICATIONS?

  • Blindness
  • Damage to nerves
  • Blood clots

TREATMENT FOR THE INFECTION

An early identification of the symptoms and timely treatment can help in successfully treating the infection. The use of specific anti-fungal medicines when administered properly can cure the disease. The most commonly used medicines include Amphotericin B which is used for severe fungal infections. However, it is strongly advised that self-medication must be avoided.

PREVENTIVE MEASURES WE CAN TAKE FROM OUR END

  1. Wearing a mask while venturing out especially to garbage dumping, garden, dusty areas etc.
  2. Avoiding over exposure of skin.
  3. The blood glucose must be constantly monitored and controlled.
  4. Maintaining proper personal hygiene.
  5. One must follow the correct amount of steroids to be taken as advised by your physician.
  6. Ensure that clean water is filled in the humidifier for those who use oxygen cylinders.

RELEVANT LINKS: https://www.healthline.com/health/mucormycosis

https://www.indiatoday.in/coronavirus-outbreak/story/mucormycosis-amphotericin-b-drug-shortage-symptoms-treatment-1803854-2021-05-18