MUCORMYCOSIS-A NEW ENTRANT

In the present condition where the second wave of coronavirus is alarming the whole world, something new has also barged in and is becoming a cause of worry-Mucormycosis. The Black fungus or “mucormycosis” in medical parlance is a new entrant into India, a rare and dangerous infection caused by a fungus by name “mucor” which can found on wet surfaces in general. These fungi are generally not harmful unless one has a weakened immune system. Black fungus is caused by mold found in moist places like soil or compost and are all pervasive in the environment. Black fungus attacks the respiratory tract. It is not contagious and does not spread from person to person. People get infected with mucromycosis , which are of several types, by breathing in fungal spores. Many people who were infected by COVID-19 were being infected by this deadly fungus due to low immune systems.

HOW DANGEROUS IS BLACK FUNGUS?

This disease is globally distributed , however its exact estimate couldn’t be placed due to insufficient data. Mucormycosis can become life threatening when it reaches the brain so doctors have to surgically remove eyes of patients to stop the infection from spreading too far and hence the infection needs to be detected soon and scraped off. The mortality rate considerably high in India due to delays in seeking medical attention and diagnosing the infection, and challenges and difficulties in managing the advanced stage of infection The estimates indicate that about 54% of people die of mucormycosis. Several people are also suffering from blindness as a result of this disease. The infection can also spread to other parts of your body through your blood. This is called disseminated mucormycosis. When this happens, the fungus affects organs like your spleen and heart. In severe cases, you might face several mental issues or also go into a coma. It can even be fatal at times.

WHO ARE ALL AT RISK?

  • Patients with Diabetes
  • People on immunosuppressants
  • People severely affected by COVID-19
  • People on ventilator support
  • Those with skin injury due to surgery or burns
  • Those who underwent organ transplant
  • HIV or AIDS
  • Long term steroid users
  • Premature birth or underweight birth

SYMPTOMS OF MUCORMYCOSIS

  • Fever
  • Shortness of breath
  • Chest pain
  • Cough
  • Swelling on one side of the face
  • Headache
  • Blurred or double vision
  • Sinus congestion
  • Pain in the belly
  • Nausea and vomiting
  • Diarrhea
  • Gastrointestinal bleeding
  • Blood in your stools
  • Black lesions on the bridge of the nose or inside the mouth

WHAT ARE THE COMPLICATIONS?

  • Blindness
  • Damage to nerves
  • Blood clots

TREATMENT FOR THE INFECTION

An early identification of the symptoms and timely treatment can help in successfully treating the infection. The use of specific anti-fungal medicines when administered properly can cure the disease. The most commonly used medicines include Amphotericin B which is used for severe fungal infections. However, it is strongly advised that self-medication must be avoided.

PREVENTIVE MEASURES WE CAN TAKE FROM OUR END

  1. Wearing a mask while venturing out especially to garbage dumping, garden, dusty areas etc.
  2. Avoiding over exposure of skin.
  3. The blood glucose must be constantly monitored and controlled.
  4. Maintaining proper personal hygiene.
  5. One must follow the correct amount of steroids to be taken as advised by your physician.
  6. Ensure that clean water is filled in the humidifier for those who use oxygen cylinders.

RELEVANT LINKS: https://www.healthline.com/health/mucormycosis

https://www.indiatoday.in/coronavirus-outbreak/story/mucormycosis-amphotericin-b-drug-shortage-symptoms-treatment-1803854-2021-05-18

Different Kinds of Face Masks to Protect Yourself from Covid-19

Since the beginning of this year, “masks” have been one of the top searches across Google. One common query which everybody has is that whether masks are effective and  which is the most effective kind of mask.

Face masks are generally of 3 types: Cloth masks, Surgical masks & N95 Respirators

Photo by Polina Tankilevitch on Pexels.com

Cloth masks

When people are in public places, along with distancing and hygiene, it is advised that they wear a mask since it is not possible to maintain a 6 feet distance always. Cloth masks prevent the spread of the virus to a considerable extent. These masks are recommended for the public rather than N95 respirators which are needed for frontline health workers. Cloth masks can be easily made at home at a low cost. Take two rectangular pieces of cloth and place them together. Insert elastic or rubber bands in both the sides and stich the cloth on the sides. Remember to change a cloth mask once it gets wet. While wearing and removing them, make sure to not touch the area which covers the mouth and nose. Wash your hands before and after wearing them. Although they provide less protection than surgical or n95 masks, it is known that they reduce the risk of transmission by some degree. Cloth masks can also be used in combination with a face shield for better protection. The Centres for Disease Control & Prevention (CDC) has suggested any covering and advised everyone to wear cloth masks for protection from asymptomatic patients. So these are probably the most advisable for the public till now.

Surgical masks

Photo by Karolina Grabowska

Surgical masks are disposable ones which protect us from sprays, large particle droplets and prevent the transmission of potentially infectious respiratory secretions. Surgical masks vary in design but usually they are rectangular in shape and blue in colour. The masks have a metal strip to adjust over the nose and are tied to the face with elastics at both sides. Although they are useful in protecting from the virus, there is an environmental hazard attached to it because these are disposable single use masks. So they contribute to landfill medical waste.

N95 Respirators

N95 Respirators are found to be the most effective in protecting against the virus since it can prevent the transmission of small particles by 95 percent. This includes virus and bacteria. The masks are usually circular or oval in shape and fit to the face very tightly. They must have the right fit because if they do not fit properly they can’t give full protection. These do not fit properly on people with facial hair and children. In a recent study it has been found that the masks can be re used after heating them in a covered pot or rice cooker for 30 minutes at 65 degree Celsius. The use of N95 is usually not very advisable to the public because of some reasons. First of all its not very comfortable to wear for a longer period of time. Secondly it is required for medical and frontline workers. So its very important that they remain in stock. A recent factor which emerged is that the valves on these respirators can be a risk factor and may not prevent the transmission of droplets entirely.

Apart from masks one needs to follow basic hygiene rules. Washing hands with a soap for atleast 20 seconds in a correct manner is extremely important as suggested by the World Health Organization (WHO). The use of hand rubs and sanitizers with alcohol content is also advisable. Physical distancing of 6 foot is to be maintained. The most effective way to prevent oneself is to avoid any kind of gathering or crowds.

Benefits of Apple Cider Vinegar

What is apple cider vinegar?  

Apple cider vinegar, also known as ACV is produced during fermentation of apple cider. The sugar present in the apple is fermented by yeast/bacteria which first turns it into alcohol. Further the alcohol is fermented to turn into acetic acid. Apple cider vinegar contains 4-5% of acetic acid, to which many health benefits can be attributed to. Not all apple cider vinegar is created the same, the key is to look for organic, unfiltered, raw apple cider vinegar with “mother” which indicates that it contains probiotics. 

What are the health benefits of apple cider vinegar?

It is almost magical what apple cider vinegar can do for your health.  Let’s start with a list of benefits first and then get into details. 

  1. It can improve digestion
  2. It lowers blood sugar levels
  3. It improves insulin sensitivity
  4. It reduces belly fat
  5. It helps lowers cholesterol
  6. It helps sooth sore throat
  7. It lowers blood pressure and improves heart health
  8. It prevents and decreases the risk of getting cancer and slows down the growth of cancer cells
  9. It helps people to lose weight and increases satiety

Apple cider vinegar is also packed with nutrition. Let’s take a look at its nutritional composition to see what makes apple cider vinegar so special. Apple cider vinegar contains:

  • Magnesium
  • amino acids
  • antioxidants
  • iron
  • manganese
  • phosphorus
  • only three (3) calories per tablespoon

1. Improves Digestion– Drinking apple cider vinegar everyday can help regulate the amount of acid present in your stomach, which will lead to easier digestion. Like any other fermented food, unfiltered apple cider vinegar contains healthy bacteria that helps to keep your digestive system functioning properly. 

2. Lowers blood sugar levels and helps fight Diabetes– Apple cider vinegar has the ability to improve insulin sensitivity and it also helps lower the blood sugar levels. According to a research published by American Diabetes Association, taking two tablespoons of apple cider vinegar before going to bed can reduce fasting blood sugars. 

3. Detoxifies the Liver– Apple cider vinegar increasing energy levels and improves its natural blood filtration processes by flushing the liver.                                                                                                                                                                                                    

4. Helps You Lose Weight– Apple cider vinegar also helps with weight loss as it increases satiety, feeling of being full, which can help prevent cravings.

5. Inhibits the growth of Cancer Cells.  Many studies show that apple cider vinegar has some anti-cancer benefits to it as it is an alkalizing food that restores the acid balance of the body which is important because cancer cells thrive in an acidic environment.

6.) Strengthens the bones – Apple cider vinegar aids in the process of  absorption of calcium, which is essential to building strong bones.

8.) Lowers Cholesterol– Studies show that apple cider vinegar reduces the bad cholesterol- LDL and in turn increases the good cholesterol- HDL due to the natural antioxidants present in it.

How to incorporate apple cider vinegar into your diet?  

The best way to incorporate apple cider vinegar into your diet is to use it for salad dressings or dilute it in water and drink it as a beverage. 1–2 tablespoons (15–30 ml) mixed in a large glass of water and consumed daily.

Refer to this article for detailed consumption patterns for different uses- Apple Cider Vinegar Dosage: How Much Should You Drink per Day?

It’s best to start with small doses of apple cider, avoid taking large amounts because too much of vinegar can cause harmful side effects.

Biotechnology is underrated!

33 Best Masters Biotechnology Programs for Commercialization and ...

Everyday, we see advances in almost everything around us. Not just technological advancements but even in living organisms as they continue to evolve with time. From the smallest microorganisms to more complex human beings, every living thing is upgrading just to survive as the living conditions become harsher. After the Covid-19 outbreak, it can be certainly said that new infectious organisms are also on the rise somewhere, waiting for their turn to enter the human world. Species are becoming extinct at a much faster rate due to human interference, lack of benevolence, and greed. With these developments, the role of biotechnology has become more significant than ever.

Biotechnology is the modification and usage of living organisms for various purposes like agricultural, industrial, and healthcare. We know that microorganisms like yeast help us in making bread and Lactobacillus leads to curdling of milk and they have been there for a long time now but now we know that there are several other such living organisms that have the potential to make lives better. These organisms are capable of doing work that are more important than making a loaf of bread or a bowl of milk but the fact that they can save lives! Biotechnology isn’t even about only these organisms but also human beings in which genetic manipulation is definitely complicated but not impossible.

In the field of agriculture and animal husbandry, biotechnology has made it possible for farms to raise both disease resistant plants and animals that are also more resilient to changing environmental conditions. The population is growing rapidly and food shortage is a major concern. With the aid of biotechnology, it is possible to ensure that no man, woman or child goes to bed hungry through enhanced productivity of crops and animals that take up less space and resources. The new farming methods also need to be environmentally sustainable so as they are not burdensome on mother earth and nature. The practices and manipulation must not take the dignity of species that can’t even speak out their concerns, for granted and humanity and empathy must persist. 

The healthcare has also been benefited by introduction of more effective medications and drugs that are biotechnologically synthesised and pose lesser risks of contamination and side effects. Gene testing and manipulation has made it possible to diagnose, prevent and even cure diseases that are inheritable. Various substances like insulin that are synthesised by the body can also be synthesised using genetically modified organisms and can aid the people that are unable to synthesise them due to underlying medical conditions. Biotechnology can also be applied to industrial processes to manufacture products that are important for human beings. Not just that, renewable sources of energy can be generated using biotechnology and can replace fossil fuels in industries. The industrial waste can be treated using genetically modified organisms until the waste is not hazardous when it is released into the environment.

Biotechnology has innumerable applications and the fact that it is a comparatively new field, a lot of research still needs to be done and new techniques are yet to be discovered so a career in biotechnology is definitely a promising one.

Coming together in COVID-19

Since the dawn of civilisation, epidemics and pandemics have continued to haunt mankind. From the outbreak of Spanish Flu to Yellow fever, history of these pandemics dates back to the time of plague in Athens (430 B.C).But perhaps; COVID-19 (spread by SARS-COV-2 virus) is greatest in the history of mankind. This particular virus has brought entire world to a halt, something that the modern world history hasn’t witnessed before.

The virus, whose roots can be traced back to Hubei Province in China, has spread globally causing the infected number of cases rising over 92 lakh. From the Superpowers to third world countries, this virus has brought down healthcare sector, economies and the entire human race on its knees; India being no exception. Yes, various sectors such as healthcare, education, energy, and logistics have faced a serious crunch amidst lockdown. With the global economy shrinking to an all time low, economists predict a depression like situation in the near future. One might question whether we are heading towards an inevitable crisis? Or is the humanity doomed? Such negative thoughts do more harm to us than the virus itself.

Just like all other major turmoil and struggles, COVID-19 too comes with its own share of lessons and learning for the mankind. Lessons in humility, humanity and gratitude. These simple lessons which we had long forgotten in the rat race for materialistic pleasures.  While some countries initially played the “blame game” but very soon they realized that the mightiest weapon in combating the virus lies in unity and mutual co-operation. Shunning the geo-political differences, the SAARC countries came together and contributed to the COVID-19 relief fund. Other stories include those of Hindu-Muslim harmony in Telangana where a group of Muslim men performed the last rituals of a Hindu woman in the middle of lockdown restrictions. This virus has brought out heart warming stories of real heroes to the forefront. From the generous acts of donating her education savings by 13 yr old Nethra of Madurai, few Jamatis voluntarily coming forward to donate plasma serve as a ray of hope in these turbulent times.

Despite the social distancing, humanity is coming closer than ever before with a mutual sense of compassion, empathy and concern towards fellow human beings.  While we stay hidden indoors amidst fear, the mother earth is breathing back to life. Those little sparrows playing in my balcony, which I hadn’t seen in a long while, are a living testimony to that. The medical staff, sanitation workers and the COVID warriors whom we once took for granted are risking their lives to save ours. What else could be a nobler act than this!

The corona virus has indeed enabled us to look beyond economic differences. Becoming more sensitive and considerate towards our domestic helps. We’ve begun appreciating simple acts of kindness, engaging in deep conversations with our loved ones and clapping to say “thank you”. Our generation is more enlightened than ever before with the realisation however evolved the human race might become but in the end we’ll only remain a tiny speck in the universe. The forces of natural world are far mightier than we could possibly become. Humans may change the course of nature but can’t defy it.

The Chinese symbol “Yin and Yang” illustrates the philosophy of life beautifully. Life flows when energies complement rather than contradict each other. The mankind and nature must maintain balance for life to exist .The day we try to overpower the forces of natural world; it will only take a single microcosmic organism to perish the entire human race.

Yin and yang: business and IT | CIO

No, I’m not implying living in a utopian world and becoming ignorant of this deadly virus .True that our healthcare and education systems have failed required to meet necessary standards. But if it wasn’t for COVID-19, these loopholes might have gone neglected. There is no better time to reshape the economy, healthcare, politics and culture than now for the dawn of new world post COVID-19.

But why did it take a virus for this realisation?

Because sometimes we need to get sick in order to get better”.

Let’s change our outlook towards this pandemic. Instead of perceiving it as a threat we need to see it as opportunity and emerge stronger than ever before. We are a fortunate generation having the privilege to shape a better world than the one we left behind. All we need is to shed stigmas and embrace this change.

Concluding in the words of Yuval Noah Harrai (bestselling author of Sapiens)

“The storm will pass, humankind will survive, most of us will still be alive –but we will inhabit a different world.”