The therapy aims at using antibodies from the blood of a recovered COVID-19 patient to treat those critically infected by the virus. Plasma is a blood component that contains virus-fighting antibodies. It is like blood donation, however, in the same plasma gets separated from the blood and the remaining blood will be transferred back to your body resulting in zero blood loss. The procedure is completely harmless and the donor does not experience any pain, sickness or dizziness.
plasma, the clear liquid component of whole blood, is collected during donation through a process known as plasmapheresis. During plasmapheresis, an apheresis machine removes and separates the plasma from the whole blood. As plasma contains nutrients, proteins, and antibodies, it can be used to develop treatments for diseases. Plasma used for these purposes is called convalescent plasma.
Convalescent plasma has been used in the prevention and treatment of infectious diseases for centuries. It is considered a form of ‘passive immunization’ as plasma collected from patients who have recovered from a previous infection and developed adaptive immunity, demonstrated by the presence of antigen-specific antibodies. Upon transfusion into another patient, the plasma can neutralize the disease pathogen, eventually eradicating it from blood circulation